14 research outputs found

    Linking Employee Stakeholders to Environmental Performance: The Role of Proactive Environmental Strategies and Shared Vision

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    Drawing on the natural-resource-based view (NRBV), we propose that employee stakeholder integration is linked to environmental performance through firms’ proactive environmental strategies, and that this link is contingent on shared vision. We tested our model with a cross-country and multi-industry sample. In support of our theory, results revealed that firms’ proactive environmental strategies translated employee stakeholder integration into environmental performance. This relationship was pronounced for high levels of shared vision. Our findings demonstrate that shared vision represents a key condition for advancing the corporate greening agenda through proactive environmental strategies. We discuss implications for the CSR and the environmental management literatures, with a particular focus on the NRBV and stakeholder integration debates

    Ectomycorrhizal fungal communities of native and non-native Pinus and Quercus species in a common garden of 35-year-old trees

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    Non-native tree species have been widely planted or have become naturalized in most forested landscapes. It is not clear if native trees species collectively differ in ectomycorrhizal fungal (EMF) diversity and communities from that of non-native tree species. Alternatively, EMF species community similarity may be more determined by host plant phylogeny than by whether the plant is native or non-native. We examined these unknowns by comparing two genera, native and non-native Quercus robur and Quercus rubra and native and non-native Pinus sylvestris and Pinus nigra in a 35-year-old common garden in Poland. Using molecular and morphological approaches, we identified EMF species from ectomycorrhizal root tips and sporocarps collected in the monoculture tree plots. A total of 69 EMF species were found, with 38 species collected only as sporocarps, 18 only as ectomycorrhizas, and 13 both as ectomycorrhizas and sporocarps. The EMF species observed were all native and commonly associated with a Holarctic range in distribution. We found that native Q. robur had ca. 120% higher total EMF species richness than the non-native Q. rubra, while native P. sylvestris had ca. 25% lower total EMF species richness than non-native P. nigra. Thus, across genera, there was no evidence that native species have higher EMF species diversity than exotic species. In addition, we found a higher similarity in EMF communities between the two Pinus species than between the two Quercus species. These results support the naturalization of non-native trees by means of mutualistic associations with cosmopolitan and novel fungi

    Cut-offs and response criteria for the Hospital Universitario la Princesa Index (HUPI) and their comparison to widely-used indices of disease activity in rheumatoid arthritis

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    Objective To estimate cut-off points and to establish response criteria for the Hospital Universitario La Princesa Index (HUPI) in patients with chronic polyarthritis. Methods Two cohorts, one of early arthritis (Princesa Early Arthritis Register Longitudinal PEARL] study) and other of long-term rheumatoid arthritis (Estudio de la Morbilidad y Expresión Clínica de la Artritis Reumatoide EMECAR]) including altogether 1200 patients were used to determine cut-off values for remission, and for low, moderate and high activity through receiver operating curve (ROC) analysis. The areas under ROC (AUC) were compared to those of validated indexes (SDAI, CDAI, DAS28). ROC analysis was also applied to establish minimal and relevant clinical improvement for HUPI. Results The best cut-off points for HUPI are 2, 5 and 9, classifying RA activity as remission if =2, low disease activity if >2 and =5), moderate if >5 and <9 and high if =9. HUPI''s AUC to discriminate between low-moderate activity was 0.909 and between moderate-high activity 0.887. DAS28''s AUCs were 0.887 and 0.846, respectively; both indices had higher accuracy than SDAI (AUCs: 0.832 and 0.756) and CDAI (AUCs: 0.789 and 0.728). HUPI discriminates remission better than DAS28-ESR in early arthritis, but similarly to SDAI. The HUPI cut-off for minimal clinical improvement was established at 2 and for relevant clinical improvement at 4. Response criteria were established based on these cut-off values. Conclusions The cut-offs proposed for HUPI perform adequately in patients with either early or long term arthritis

    Treatment with tocilizumab or corticosteroids for COVID-19 patients with hyperinflammatory state: a multicentre cohort study (SAM-COVID-19)

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    Objectives: The objective of this study was to estimate the association between tocilizumab or corticosteroids and the risk of intubation or death in patients with coronavirus disease 19 (COVID-19) with a hyperinflammatory state according to clinical and laboratory parameters. Methods: A cohort study was performed in 60 Spanish hospitals including 778 patients with COVID-19 and clinical and laboratory data indicative of a hyperinflammatory state. Treatment was mainly with tocilizumab, an intermediate-high dose of corticosteroids (IHDC), a pulse dose of corticosteroids (PDC), combination therapy, or no treatment. Primary outcome was intubation or death; follow-up was 21 days. Propensity score-adjusted estimations using Cox regression (logistic regression if needed) were calculated. Propensity scores were used as confounders, matching variables and for the inverse probability of treatment weights (IPTWs). Results: In all, 88, 117, 78 and 151 patients treated with tocilizumab, IHDC, PDC, and combination therapy, respectively, were compared with 344 untreated patients. The primary endpoint occurred in 10 (11.4%), 27 (23.1%), 12 (15.4%), 40 (25.6%) and 69 (21.1%), respectively. The IPTW-based hazard ratios (odds ratio for combination therapy) for the primary endpoint were 0.32 (95%CI 0.22-0.47; p < 0.001) for tocilizumab, 0.82 (0.71-1.30; p 0.82) for IHDC, 0.61 (0.43-0.86; p 0.006) for PDC, and 1.17 (0.86-1.58; p 0.30) for combination therapy. Other applications of the propensity score provided similar results, but were not significant for PDC. Tocilizumab was also associated with lower hazard of death alone in IPTW analysis (0.07; 0.02-0.17; p < 0.001). Conclusions: Tocilizumab might be useful in COVID-19 patients with a hyperinflammatory state and should be prioritized for randomized trials in this situatio

    Experimental evidence of the structure of annihilation of antiphase boundaries in GaAs on Si

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    3 páginas, 2 figuras.A high-resolution electron microscopy (HREM) study on antiphase boundaries in GaAs grown on Si is presented. HREM images of two close antiphase boundaries appearing mainly on the {110} planes which abruptly disappear suggest some ideas on the mechanisms of annihilation of these defects.Peer reviewe

    Anales de Edafología y Agrobiología Tomo 44 Número 9-10

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    l. Suelos. Física. Desecación de muestras de suelo de diferente textura, en condiciones naturales. l. Evaporación y movimiento del agua, por F. lngelmo Sánchez y S. Cuadrado Sánchez.-- Desecación de muestras de suelo de diferente textura, en condiciones naturales. II. Evolución de la temperatura, por F. lngelmo Sánchez y S. Cuadrado Sánchez.-- Estudio de las propiedades hidrodinámicas de perfiles instalados en lisímetros. I. Métodos de medida y cálculo de la conductividad capilar, por A. Paz González y F. Díaz Fierros Viqueira.-- l. Suelos. Química Características químico-Mineralógicas de suelos desarrollados sobre granodioritas y granitos en la provincia de Avila, por Ma L. Cembranos Pérez.-- Estudio edafo-geoquímico de las series detrítica y evaporítica de la provincia de Madrid; l. Características morfológicas, químicas y fisico-químicas de los suelos, por A. M. Alvarez González, J. Rodríguez Sanchidrian y A. Guerra Delgado.-- Estudio edafo-qufmico de las series detrítica y evaporítica de la provincia de Madrid: II. Distribución de metales pesados en horizontes C. Diferenciación de zonas, por A. M. Alvarez González, J. Rodríguez Sanchidrián y A. Guerra Delgado.-- Identificación de un mineral interestratificado clorita-esmectita por sordón interlaminar de aminas. "Facies verdes" de la cuenca del Tajo. III., por M. Doval, M. Rodas, A. Ruiz A mil y F. Aragon de la Cruz.-- Contribución al conocimiento de la materia orgánica en suelos del Centro-Oeste de España, por A. Moyano y J. F. Gallardo.-- Interacción de los herbicidas 2,4-D y 2,4,5-T con montmorillonita Cu, por C. Rodríguez Pascual y M. S. Hernández-Crespo.-- l. Suelos. Génesis, Clasificación y Cartografía Caracterización de suelos en el sector central de la sierra del Segura (I). Sierra de Mirabueno, por J. González Parra, A. López Lafuente y C. González Huecas-- Contribución al estudio de los suelos desarrollados bajo los encinares de la provincia de Granada, por l. García Fernández, M. Simón Torres y C. Gil de Carrasco.-- Los índices de similitud y su relación con diferentes tipos de características en el análisis numérico de suelos, por L. Alcalá del Olmo B. y F. Monturiol Rodríguez.-- I. Suelos. Fertilidad Estimación del contenido en arcilla selectiva de K, mediante electroultrafiltración, por J. A. Díez.-- Efecto de la nitrapirina en la eficiencia de utilización de la uréa y rendimiento de avena, por l. Vidal, A. Herrera, M. Geldres y L. Longueri.-- Efecto de la fertilización nitrogenada y potásica sobre la producción en el cultivo del platano, por M. Fernández Falcón y R. L. Fox.-- Determinación de Nitrógeno U .V. oxidable y de Nitrato, en extractos de suelos mediante autoanalizador, por J. A. Díez.-- II. Biología Vegetal. Nutrición Composición mineral de las hojas de Aguacate (Persea americana Mili.) en plantaciones comerciales de la provincia de Málaga (España). l. Macroelementod, por S. Jaime, J. M. Farré, J. M. Hermoso y A. Aguilar.-- II. Biología Vegetal. Fisiología La sucesión secundaria a pastizales en función del efecto del arbolado (Encina y Roble), por A. Puerto, J. A. García Rodríguez, A. R. Martínez Mediavilla y A. Saldaña.-- II. Biología Vegetal. Protección Vegetal Estudio de la contaminación por metales pesados en diversas especies vegetales de la Vega de Aranjuez. (I). Distribución en las partes constitutivas, por V. Cala Rivera, y J. Rodríguez Sanchidrián.-- Estudio de la contaminación por metales pesados en diversas especies vegetales de la Vega de Aranjuez. (II). Potencial toxicidad, por V. Cala Rivero y J. Rodríguez Sanchidrián.-- II. Biología Vegetal. Agrobiología Leguminosas y gramíneas como base para la tipificación de pastos. l. Prados de la montaña de Teruel, por A. Gómez Sal, S. Oliver Moscardó y J. Pastor PiñeiroPeer reviewe

    <i>RENACER</i> Study: Assessment of 12-month efficacy and safety of 168 certolizumab-PEGol rheumatoid arthritis treated patients from a Spanish multicenter National database.

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    <div><p></p><p><b>Objective:</b> To assess effectiveness and safety of certolizumab PEGol (CZP) in Rheumatoid Arthritis (RA) patients after 12 months of treatment and to detect predictors of response.</p><p><b>Methods:</b> Observational longitudinal prospective study of RA patients from 35 sites in Spain. Variables (baseline, 3- and 12-month assessment): socio-demographics, previous DMARD and previous Biological Therapies (BT) use; TJC, SJC, ESR, CRP, DAS28, SDAI. Response variables: TJC, SJC, CRP, ESR and steroids dose reductions, EULAR Moderate/Good Response, SDAI response and remission, DAS28 remission. Safety variables: discontinuation due to side-effects. Descriptive, comparative and Logistic regression analyses were performed.</p><p><b>Results:</b> We included 168 patients: 79.2% women, mean age 54.5 years (±13.2 SD), mean disease duration 7.5 years (±7.3 SD). Mean number of prior DMARD: 1.4 (±1.2 SD), mean number of prior BT was 0.8 (±1.1). Mean time on CZP was 9.8 months (±3.4 SD). A total of 71.4% were receiving CZP at 12-month assessment. Baseline predictors of response: lower prior number DMARD; low number prior BT; higher CRP, ESR, TJC, SJC, DAS28 and SDAI (p<0.05) scores. A 25/46.4% Moderate/Good Response, a 20% SDAI remission, and a 44% DAS28 remission were observed. We observed 48 discontinuations (28.6%), 31 due to partial or complete ineffectiveness and 17 due to side-effects.</p><p><b>Conclusions:</b> CZP showed benefit in severe RA patients, with significant reduction of all effectiveness parameters, despite the high prevalence of previous BT exposure in our series. We found CRP, ESR, prior DMARD/BT number, TJC, SJC, DAS28, and SDAI as baseline predictors of response. CZP was mostly well tolerated.</p></div
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